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KMID : 0360220080490071078
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Journal of the Korean Ophthalmological Society
2008 Volume.49 No. 7 p.1078 ~ p.1086
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Photodynamic Therapy with Vertepofin for Short Time for Chronic Central Serous Chorioretinopathy
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Kim Jung-Lim
Kim Hyun-Woong
Yun Il-Han
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Abstract
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Purpose: To evaluate the clinical results of short duration photodynamic therapy (PDT) using verteporfin in patients with chronic central serous chorioretinopathy (CSC).
Methods: We retrospectively examined 15 eyes after PDT for chronic central serous chorioretinopathy. PDT for 83 seconds was evaluated for 8 eyes, and PDT for 60 seconds was evaluated for 7 eyes. Improvement in vision and changes in central macular thickness were evaluated with an optical coherence tomogram (OCT), and improvement in leaking was evaluated with a fluorescein angiogram (FA). Recurrence was also studied.
Results: Visual acuity improved from 0.39 to 0.57 (p=0.04), and the mean central macular thickness decreased from 426.29 μm to 184.71 μm (p<0.01) in 7 eyes treated with PDT for 60 seconds. There was no significant change in visual acuity between the two groups (p=0.77) or in central macular thickness (p=0.52). Central macular exudation resolved completely in all eyes. After PDT, there was no recurrence during the follow-up period.
Conclusions: Short duration PDT with verteporfin appears to be a beneficial treatment option for patients with chronic CSC. J Korean Ophthalmol Soc 49(7):1078-1086, 2008
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KEYWORD
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Chronic centralserouschorioretinopathy, Indocyaninegreenangiography, Opticalcoherencetomography, Photodynamictherapy
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